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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKN3
All Species:
23.03
Human Site:
S445
Identified Species:
36.19
UniProt:
Q6P5Z2
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P5Z2
NP_037487.2
889
99421
S445
G
Q
D
F
L
R
A
S
Q
M
N
L
G
M
A
Chimpanzee
Pan troglodytes
XP_001159776
886
99121
S442
G
Q
D
F
L
R
A
S
Q
M
N
L
G
M
A
Rhesus Macaque
Macaca mulatta
XP_001110500
1011
111864
S558
G
Q
D
F
L
R
A
S
Q
M
N
L
S
M
A
Dog
Lupus familis
XP_548434
951
104664
S507
G
Q
D
F
L
R
A
S
Q
M
N
L
S
M
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8K045
878
97863
S438
G
R
D
F
M
R
A
S
Q
M
N
L
S
M
A
Rat
Rattus norvegicus
O08874
985
112050
P509
G
K
T
F
L
R
A
P
Q
M
N
I
N
I
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506565
993
109767
S546
G
Q
D
F
L
R
A
S
Q
M
N
I
N
I
V
Chicken
Gallus gallus
XP_422357
1013
114806
P534
G
K
T
F
L
R
A
P
Q
M
N
I
N
I
A
Frog
Xenopus laevis
Q7ZX15
486
56292
D119
L
K
N
Q
V
P
E
D
E
E
E
E
A
M
E
Zebra Danio
Brachydanio rerio
XP_697542
940
106140
A496
G
K
N
F
L
R
A
A
Q
M
N
M
N
F
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
M267
L
A
T
S
T
T
T
M
T
S
G
Y
N
S
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
K326
M
S
I
R
S
K
K
K
P
S
I
M
T
D
T
Sea Urchin
Strong. purpuratus
XP_787090
799
90414
G334
G
K
N
F
L
R
A
G
Q
M
N
I
N
V
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
A562
K
K
R
T
V
P
S
A
Q
L
G
S
S
I
G
Red Bread Mold
Neurospora crassa
P87253
1142
127954
S616
L
R
P
G
S
K
T
S
I
S
S
G
S
I
A
Conservation
Percent
Protein Identity:
100
97.7
81.5
84.2
N.A.
83.2
49.9
N.A.
64.2
48.9
26.2
52.2
N.A.
28
N.A.
29.1
41.5
Protein Similarity:
100
97.8
82.9
87.6
N.A.
88.4
63.6
N.A.
72.9
63
36.6
67.6
N.A.
41.5
N.A.
43.9
58.2
P-Site Identity:
100
100
93.3
93.3
N.A.
80
60
N.A.
73.3
60
6.6
60
N.A.
0
N.A.
0
60
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
80
N.A.
86.6
80
33.3
86.6
N.A.
6.6
N.A.
13.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.2
27.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.7
43.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
0
67
14
0
0
0
0
7
0
67
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
40
0
0
0
0
7
0
0
0
0
0
7
0
% D
% Glu:
0
0
0
0
0
0
7
0
7
7
7
7
0
0
7
% E
% Phe:
0
0
0
67
0
0
0
0
0
0
0
0
0
7
0
% F
% Gly:
67
0
0
7
0
0
0
7
0
0
14
7
14
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
0
0
0
0
0
7
0
7
27
0
34
0
% I
% Lys:
7
40
0
0
0
14
7
7
0
0
0
0
0
0
0
% K
% Leu:
20
0
0
0
60
0
0
0
0
7
0
34
0
0
0
% L
% Met:
7
0
0
0
7
0
0
7
0
67
0
14
0
40
0
% M
% Asn:
0
0
20
0
0
0
0
0
0
0
67
0
40
0
0
% N
% Pro:
0
0
7
0
0
14
0
14
7
0
0
0
0
0
0
% P
% Gln:
0
34
0
7
0
0
0
0
74
0
0
0
0
0
0
% Q
% Arg:
0
14
7
7
0
67
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
7
0
7
14
0
7
47
0
20
7
7
34
7
7
% S
% Thr:
0
0
20
7
7
7
14
0
7
0
0
0
7
0
7
% T
% Val:
0
0
0
0
14
0
0
0
0
0
0
0
0
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _